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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SHANK1
All Species:
5.45
Human Site:
S490
Identified Species:
13.33
UniProt:
Q9Y566
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y566
NP_057232.2
2161
224959
S490
S
G
T
L
R
S
A
S
S
P
R
G
A
R
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001099818
1269
136588
Dog
Lupus familis
XP_541475
1171
125680
Cat
Felis silvestris
Mouse
Mus musculus
Q4ACU6
1805
192199
G303
Y
H
S
A
L
G
G
G
D
A
L
C
C
E
L
Rat
Rattus norvegicus
Q9WV48
2167
226317
S490
S
G
T
L
R
S
A
S
S
P
R
G
A
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507367
1367
148107
Chicken
Gallus gallus
XP_426415
1770
194380
I268
S
G
N
T
A
L
H
I
C
A
L
Y
N
Q
E
Frog
Xenopus laevis
Q52KW0
1292
141161
Zebra Danio
Brachydanio rerio
NP_001121819
1800
196374
Y298
E
I
H
Q
A
C
R
Y
G
H
V
Q
H
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610925
1871
198983
S367
R
Y
N
P
K
R
R
S
G
I
G
W
L
S
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
23.2
52
N.A.
39.1
93.3
N.A.
26.7
39.1
22.5
37.8
N.A.
22.6
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
33.4
53.2
N.A.
49.8
95.1
N.A.
35.4
50.8
34
50.5
N.A.
35.1
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
0
0
N.A.
0
100
N.A.
0
13.3
0
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
0
0
N.A.
6.6
100
N.A.
0
20
0
0
N.A.
20
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
20
0
20
0
0
20
0
0
20
0
30
% A
% Cys:
0
0
0
0
0
10
0
0
10
0
0
10
10
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
0
0
0
0
0
0
10
20
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
30
0
0
0
10
10
10
20
0
10
20
0
0
0
% G
% His:
0
10
10
0
0
0
10
0
0
10
0
0
10
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
20
10
10
0
0
0
0
20
0
10
10
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
20
0
0
0
0
0
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
0
20
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
10
0
10
0
% Q
% Arg:
10
0
0
0
20
10
20
0
0
0
20
0
0
20
0
% R
% Ser:
30
0
10
0
0
20
0
30
20
0
0
0
0
10
0
% S
% Thr:
0
0
20
10
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
10
10
0
0
0
0
0
10
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _